Polygenic Embryo ELSI Research
The "PEER" Group
Scientific Literature
Reviews
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R. Smolarczyk, …, and E. Adashi. Foretelling the Future: Preimplantation Genetic Testing and the Coming of Polygenic Embryo Screening. Journal of Clinical Medicine (2025).
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A. Roura-Monllor, …, S. Carmi, T. Lencz, and R. B. Lathi. Promises and pitfalls of preimplantation genetic testing for polygenic disorders: a narrative review. F&S Reviews (2025)
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M. Siermann, J. R. Vermeesch, T. Raivio, O. Tšuiko, and P. Borry. Polygenic embryo screening: quo vadis? Journal of Assisted Reproduction and Genetics (2024).
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A. Capalbo, G. de Wert, H. Mertes, L. Klausner, …, K. Sermon, N. Vermeulen, T. Lencz, and S. Carmi. Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations. Human Reproduction Update (2024).
Related: Too early for clinics to introduce polygenic embryo screening (PES). Fiona MacRae, Focus on Reproduction (ESHRE) (2024).
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D. K. Griffin and A. T. Gordon. Preimplantation Testing for Polygenic Disease (PGT-P): Brave New World or Mad Pursuit? DNA (2023).
A. Polyakov, D. J. Amor, …, Y. Mizrachi, and G. Rozen. Polygenic risk score for embryo selection—not ready for prime time. Human Reproduction (2022).
N. R. Treff, J. Savulescu, I. de Melo-Martin, L. P. Shulman, and E. C. Feinberg. Should preimplantation genetic testing for polygenic disease be offered to all – or none? Fertility and Sterility (2022).
Commentaries
Genetic justice: Polygenic scores and ethnic differences. Genetic Literacy Project. Jonathan Anomaly. February 21, 2024.
Genetic embryo screening for health issues and IQ inch closer to reality. Here’s a primer on what you can expect. Genetic Literacy Project. Barbara Pfeffer Billauer. March 7, 2024.
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X. Wu, J. Pan, Y. Zhu, and H. Huang. Research progress and challenges of preimplantation genetic testing for polygenic diseases. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023 Nov 20:1-8.
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E. Y. Adashi. D. P. O’Mahony, and I. G. Cohen. Preimplantation Polygenic Risk Score Testing Is Unvalidated And Unregulated (2023)
C. B. Ogbunugafor and M. D. Edge. GATTACA as a lens of contemporary genetics: Marking 25 years into the film’s “not-too-distant” future. (2022)
L. C. A. M. Tellier, J. Eccles, N. R. Treff, L. Lello, S. Fishel, and S. Hsu. Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations. Genes (2021).
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N. R. Treff. Polygenic risk scoring in the human embryo: reproductive genetics, final frontier? F&S Science. (2020)
B. Jordan. Polygenic scores: towards designer babies? Médecine/sciences (2020) (French)